Mirena IUD & Postmenopausal Women

Introduction
As we age, our bodies undergo significant hormonal shifts, particularly during menopause. Many women turn to hormone replacement therapy (HRT) to restore balance, improve energy, and protect long-term health. However, if you have a Mirena IUD in place, you may unknowingly be disrupting your hormone optimization—and potentially increasing certain health risks. At Tarpon Springs Wellness Center, we are committed to educating women on the best approaches to HRT, and for many postmenopausal women, removing the Mirena IUD is a necessary first step.
Understanding the Mirena IUD and Its Role in Hormonal Health
The Mirena IUD is a levonorgestrel-releasing intrauterine device designed primarily for birth control and reducing heavy menstrual bleeding. It works by releasing synthetic progestin (levonorgestrel) into the uterus, which:
- Thickens cervical mucus to prevent sperm from reaching the egg.
- Thins the endometrial lining to reduce bleeding.
- Suppresses ovulation in some women (but not all).
While this can be beneficial for women of childbearing age, postmenopausal women do not need birth control and, more importantly, may experience negative effects from synthetic hormones like levonorgestrel.

Why the Mirena IUD is Ineffective and Potentially Harmful for Postmenopausal Women
If you are postmenopausal and still have a Mirena IUD, here’s why it may be interfering with your hormonal health and HRT treatment:
1. Insufficient Hormonal Support for Postmenopausal Women:
The Mirena IUD does not offer adequate hormonal support for a postmenopausal woman. The minimal progestin it releases is insufficient to properly balance estrogen levels, potentially resulting in unopposed estrogen. This imbalance may increase the risk of conditions such as endometrial hyperplasia and estrogen dominance.
2. Disrupts the Natural Balance of Hormones:
For women transitioning into menopause, the body naturally stops producing progesterone and estrogen in large amounts. The Mirena IUD releases synthetic progestin, which does not behave the same way as bioidentical progesterone. Instead of balancing estrogen, it can create hormonal imbalances that interfere with mood, sleep, metabolism, and energy levels.
3. Increased Health Risks: Blood Clots, Cancer, and Cardiovascular Disease
Studies have shown that synthetic progestins, like those in Mirena, can increase the risk of:
- Blood Clots – Synthetic hormones may contribute to an increased risk of venous thromboembolism (VTE).
- Breast Cancer – Prolonged use of synthetic progestins has been linked to an increased risk of hormone-driven cancers.
- Cardiovascular Disease – Hormonal imbalances caused by the Mirena IUD can affect lipid metabolism and blood pressure, increasing heart disease risks in postmenopausal women.
- Blood Clots – Synthetic hormones may contribute to an increased risk of venous thromboembolism (VTE).
4. Complicates Proper Dosing of HRT
One of the biggest reasons we recommend removing the Mirena IUD before starting HRT is that it makes it difficult to properly balance and dose the following essential hormones:
- Testosterone – Necessary for muscle strength, libido, mood, and energy.
- Estradiol – Crucial for protecting bones, heart health, and brain function.
- Micronized Progesterone (Bioidentical) – Needed to counterbalance estrogen and support sleep, mood, and metabolism.
- Testosterone – Necessary for muscle strength, libido, mood, and energy.
Since the levonorgestrel in Mirena does not function like real progesterone, it creates misleading lab results and makes it harder to optimize HRT, leaving many women underdosed or overdosed on critical hormones.

What’s the Solution? Removing the Mirena IUD for Optimal Hormone Balance
The best way to ensure accurate hormone testing and effective HRT treatment is to remove the Mirena IUD. Once removed, we can assess your true hormone levels and create a customized HRT plan using bioidentical hormones that work naturally with your body.
At Tarpon Springs Wellness Center, we specialize in personalized hormone therapy to help women regain vitality, balance, and well-being. If you have a Mirena IUD and are considering HRT, we strongly encourage you to discuss removal options with us.

Next Steps
✔️ Schedule a consultation with us here.
✔️ Get a comprehensive hormone evaluation.
✔️ Begin a tailored HRT protocol based on your lab work using bioidentical estradiol, progesterone, and testosterone.
✔️ Monitor your progress with expert guidance.
Your health and well-being are our top priority. We are here to guide you through the transition into a balanced, vibrant postmenopausal life.
📞 Call us today at 727-279-0067 with any questions or to book a consultation over the phone.
For further reading on the risks of synthetic hormones and the benefits of bioidentical HRT:
Journal of Clinical Oncology – Synthetic Progestins and Cancer Risk
British Medical Journal – Hormonal IUDs and Blood Clot Risks
British Medical Journal - Arterial Thrombosis in Users of Contemporary Hormonal Contraception
The Lancet – Hormone Replacement Therapy and Long-Term Benefits